abstract：:"Frontiers in Fontan Failure" was the title of a 2015 conference sponsored by Children's Healthcare of Atlanta and Emory University School of Medicine. In what is hoped to be the first of many such gatherings, speakers and attendees gathered to discuss the problem of long-term clinical deterioration in these patients....

journal_title：Congenital heart disease

authors： Hebson C,Book W,Elder RW,Ford R,Jokhadar M,Kanter K,Kogon B,Kovacs AH,Levit RD,Lloyd M,Maher K,Reshamwala P,Rodriguez F,Romero R,Tejada T,Marie Valente A,Veldtman G,McConnell M

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To provide data on the value of fused cardiac hybrid imaging with coronary computed tomography angiography (CCTA) and positron emission tomography myocardial perfusion imaging (PET-MPI) in patients with complex coronary artery anomalies (CCAA). DESIGN/SETTING:This is a retrospective, single-center study. PA...

journal_title：Congenital heart disease

authors： Gräni C,Benz DC,Possner M,Clerc OF,Mikulicic F,Vontobel J,Stehli J,Fuchs TA,Pazhenkottil AP,Gaemperli O,Kaufmann PA,Buechel RR

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Intravascular stents are now routinely used to treat young patients with vascular stenoses. Future stent redilations are often necessary to account for somatic growth. The purpose of this study was to compile a database of characteristics for stents commonly used in the treatment of congenital heart disease p...

journal_title：Congenital heart disease

authors： Danon S,Gray RG,Crystal MA,Morgan G,Gruenstein DH,Goldstein BH,Gordon BM

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Perturbations in the CACNA1C-encoded L-type calcium channel α-subunit have been linked recently to heritable arrhythmia syndromes, including Timothy syndrome, Brugada syndrome, early repolarization syndrome, and long QT syndrome. These heritable arrhythmia syndromes may serve as a pathogenic basis for auto...

journal_title：Congenital heart disease

authors： Sutphin BS,Boczek NJ,Barajas-Martínez H,Hu D,Ye D,Tester DJ,Antzelevitch C,Ackerman MJ

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Determine the accuracy of echocardiography to diagnose coronary anatomy in transposition of the great arteries and to evaluate the effect of accuracy on surgical outcomes and changes in accuracy over time. DESIGN:Retrospective chart review of neonates admitted February 1999 to March 2013 with transposition. ...

journal_title：Congenital heart disease

authors： Fundora MP,Aregullin EO,Wernovsky G,Welch EM,Muniz JC,Sasaki N,Hannan RL,Burke RP,Lopez L

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:To determine if patients evaluated using the pediatric chest pain standardized clinical assessment and management plan (SCAMP) in cardiology clinic were later diagnosed with unrecognized cardiac pathology, and to determine if other patients with cardiac pathology not enrolled in the SCAMP would have been ide...

journal_title：Congenital heart disease

authors： Kane DA,Friedman KG,Fulton DR,Geggel RL,Saleeb SF

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To assess how obesity or diabetes mellitus impacts outcomes in patients undergoing cardiac surgery in pediatric hospitals. DESIGN:A multi-institutional, matched case-control study of the Pediatric Health Information System database was performed. SETTING:Tertiary children's hospitals in the United States. ...

journal_title：Congenital heart disease

authors： Shamszad P,Rossano JW,Marino BS,Lowry AW,Knudson JD

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Left cardiac sympathetic denervation (LCSD) exerts significant antifibrillatory effects in patients with long QT syndrome (LQTS). Recently, electromechanical window (EMW) has emerged as a novel torsadogenic marker in LQTS, superior to QT interval (QTc) in distinguishing symptomatic from asymptomatic patients...

journal_title：Congenital heart disease

authors： Schneider AE,Bos JM,Ackerman MJ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Open cardiac surgery has traditionally been the gold standard for repair of ventricular septal defect (VSD). The inherent risks and complications associated with open surgery and the incidence of postoperative residual VSD are significant disadvantages of the open surgical approach. OBJECTIVE:To evaluate th...

journal_title：Congenital heart disease

authors： Zhou W,Li F,Fu L,Gao W,Guo Y,Liu T,Huang M,Zhang Y

更新日期：2016-07-01 00:00:00

abstract：:As physicians and caregivers of children with congenital heart disease, we are aware of the increasing need for procedures requiring anesthesia. While these procedures may be ideal for medical and cardiac surgical management, the risks and benefits must be assessed carefully. There are well known risks of cardiovascul...

journal_title：Congenital heart disease

authors： Char D,Ramamoorthy C,Wise-Faberowski L

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients who underwent a successful repair of the aortic coarctation show chronic hyperdynamic state and normal left ventricular (LV) geometry; however, there are few data regarding the LV systolic function in the long term. Accordingly, we assessed LV systolic mechanics and factors associated with ...

journal_title：Congenital heart disease

authors： Faganello G,Fisicaro M,Russo G,Iorio A,Mazzone C,Grande E,Humar F,Cherubini A,Pandullo C,Barbati G,Tarantini L,Benettoni A,Pozzi M,Di Lenarda A,Cioffi G

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Atrial septal defect (ASD) is the second most common congenital heart defect (CHD) and is observed in families as an autosomal dominant trait as well as in nonfamilial CHD. Mutations in the NKX2-5 gene, located on chromosome 5, are associated with ASD, often combined with conduction disturbances, cardiomyopat...

journal_title：Congenital heart disease

authors： Ellesøe SG,Johansen MM,Bjerre JV,Hjortdal VE,Brunak S,Larsen LA

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Arterial switch operation has become the treatment of choice for neonates with transposition of the great arteries. The most important step of the procedure is transferring the coronary arteries to the neoaorta successfully. This study shows the impact of coronary anatomy on early mortality and morbidity afte...

journal_title：Congenital heart disease

authors： Altin FH,Sengul FS,Yildiz O,Tosun O,Ozturk E,Kyaruzi M,Cine N,Guzeltas A,Yeniterzi M,Bakir İ

更新日期：2016-03-01 00:00:00

abstract：:So-called heterotaxy affects lateralization of the thoracic and abdominal organs. Congenital malformations may be present in one of several organ systems. Cardiac involvement includes both structural and conduction abnormalities. Data regarding arrhythmias in heterotaxy come from case reports and small case series. We...

journal_title：Congenital heart disease

authors： Loomba RS,Willes RJ,Kovach JR,Anderson RH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Recent advances in various disciplines of medicine have significantly changed the courses following cardiac surgery in children. On-table extubation (OTE) after open heart surgery in children is evolving. OBJECTIVE:To assess the rate of postoperative complications in children extubated on table after open h...

journal_title：Congenital heart disease

authors： Hoda M,Haque A,Aijaz F,Akhtar MI,Rehmat A,Amanullah M,Hasan BS

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Obesity affects adults with congenital heart disease (CHD). The effect of an increased body mass index (BMI) with respect to morbidity and mortality has not been evaluated in adults with complex CHD. Our objective was to evaluate the effects of increased BMI on heart failure and mortality in univentricular pa...

journal_title：Congenital heart disease

authors： Martinez SC,Byku M,Novak EL,Cedars AM,Eghtesady P,Ludbrook PA,Billadello JJ

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to characterize the natural history of metabolic uncoupling (type B hyperlactemia and hyperglycemia) following cardiopulmonary bypass (CPB), and to determine the impact of insulin therapy on time to lactate normalization in patients without low cardiac output. DESIGN:The desig...

journal_title：Congenital heart disease

authors： Palermo RA,Palac HL,Wald EL,Wainwright MS,Costello JM,Eltayeb OM,Backer CL,Epting CL

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare neurological development of children with cyanotic or hemodynamically impaired congenital heart disease (CHD) and healthy controls by using "Bayley Scales of Infant and Toddler Development Screening Test, Third Edition" (Bayley-III). PATIENTS:Children with CHD (n = 37...

journal_title：Congenital heart disease

authors： Hallioglu O,Gurer G,Bozlu G,Karpuz D,Makharoblidze K,Okuyaz C

更新日期：2015-11-01 00:00:00

abstract：:This review synthesizes the empirical literature on outcomes and experiences of transfer and transition from pediatric to adult care for young people with congenital heart disease. A systematic review of papers published between January 2001 and May 2013 that examined outcomes or experiences of transfer and transition...

journal_title：Congenital heart disease

authors： Heery E,Sheehan AM,While AE,Coyne I

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Nurse practitioners (NPs) have an established role for delivering competent care to patients in the primary care setting. The aim of this study was to compare satisfaction of patients managed by NPs vs. physicians in the outpatient adult congenital heart disease (CHD) clinic. DESIGN:A prospective study condu...

journal_title：Congenital heart disease

authors： Maul TM,Zaidi A,Kowalski V,Hickey J,Schnug R,Hindes M,Cook S

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Deficient retro-aortic rim has been identified as a risk factor for device erosion following trans-catheter closure of atrial septal defects (ASDs). Transthoracic echocardiography (TTE) is the primary screening method for subjects for possible device closure of ASD, but its reliability in measuring retro-aort...

journal_title：Congenital heart disease

authors： O'Byrne ML,Glatz AC,Goldberg DJ,Shinohara R,Dori Y,Rome JJ,Gillespie MJ

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The electrocardiogram (ECG) is used to detect left ventricular hypertrophy (LVH) in children and young adults, and it is considered an important screening tool for the most common causes of sudden cardiac arrest in the United States. However, the reliability and accuracy of the ECG in the detection of LVH are...

journal_title：Congenital heart disease

authors： Bratincsák A,Williams M,Kimata C,Perry JC

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Heart transplant recipients are at risk for developing left ventricular (LV) dysfunction. While traditional echocardiographic parameters have limitations, speckle tracking echocardiography (STE) is a novel technique shown to be more sensitive and accurate in adult studies for evaluating ventricular systoli...

journal_title：Congenital heart disease

authors： Buddhe S,Richmond ME,Gilbreth J,Lai WW

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Traditionally, karyotype and fluorescence in situ hybridization (FISH) were used for cytogenetic testing of infants with congenital heart disease (CHD) who underwent cardiac surgery at our institution. Recently, chromosome microarray analysis (CMA) has been performed in lieu of the traditional tests. A standa...

journal_title：Congenital heart disease

authors： Buckley JR,Kavarana MN,Chowdhury SM,Scheurer MA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the effects of anesthesia by dexmedetomidine and propofol on the hemodynamics and oxygen balance in children with complex congenital heart disease who were undergoing cardiac surgery. METHODS:Fifty-seven children were randomized to receive either a continuous infusion of ...

journal_title：Congenital heart disease

authors： Cheng X,Zuo Y,Zhao Q,Gu E,Huang Y

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:Right ventricular (RV) failure and ventricular dyssynchrony are strong determinants of prognosis in patients with adult congenital heart disease (ACHD). The aim of this study was to investigate the relationship between interventricular dyssynchrony (IVD) using cine-tagged magnetic resonance imaging (MRI) and RV...

journal_title：Congenital heart disease

authors： Nagao M,Yamasaki Y,Yonezawa M,Matsuo Y,Kamitani T,Yamamura K,Sakamoto I,Abe K,Kawanami S,Honda H

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Congenital cardiac defects represent the most common group of birth defects, affecting an estimated six per 1000 births. Genetic characterization of patients and families with cardiac defects has identified a number of genes required for heart development. Yet, despite the rapid pace of these advances, mutati...

journal_title：Congenital heart disease

authors： Thorsson T,Russell WW,El-Kashlan N,Soemedi R,Levine J,Geisler SB,Ackley T,Tomita-Mitchell A,Rosenfeld JA,Töpf A,Tayeh M,Goodship J,Innis JW,Keavney B,Russell MW

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:Improved weight gain during the interstage (IS) period has been shown to improve overall outcomes in patients with single ventricle physiology (SVP). This emphasis on nutrition may have untoward effects, such as increasing anxiety/stress levels in caregivers, who are already known to be at risk for increas...

journal_title：Congenital heart disease

authors： Stewart J,Dempster R,Allen R,Miller-Tate H,Dickson G,Fichtner S,Principe AJ,Fonseca R,Nicholson L,Cua CL

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to quantitatively compare findings of emotional functioning across studies of adolescents and adults with congenital heart disease (CHD) through meta-analysis. DESIGN:The current meta-analysis included 22 studies of adolescent and adult survivors of CHD who completed measures of emotional fu...

journal_title：Congenital heart disease

authors： Jackson JL,Misiti B,Bridge JA,Daniels CJ,Vannatta K

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Following congenital heart surgery, pediatric patients may experience persistent respiratory failure that requires tracheostomy placement. Currently, definitive knowledge of the optimal timing for tracheostomy placement in this patient population is lacking. METHODS:An 8-year retrospective review of 17 pe...

journal_title：Congenital heart disease

authors： Costello JP,Emerson DA,Shu MK,Peer SM,Zurakowski D,Reilly BK,Klugman D,Jonas RA,Nath DS

更新日期：2015-01-01 00:00:00

abstract：:In patients with Kawasaki disease (KD) and coronary artery aneurysms (CAAs), serial evaluation with multiple imaging modalities is recommended to guide risk stratification and management. We present the case of a 7-year-old boy with a history of KD and multiple giant CAAs who developed thrombosis in one of the aneurys...

journal_title：Congenital heart disease

authors： Prsa M,Hussain T,McCrindle BW,Grosse-Wortmann L

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Transient elastography (TE) offers a noninvasive correlate with the degree of hepatic fibrosis. However, factors other than fibrosis affect liver stiffness. We sought to determine whether hepatic congestion related to hemodynamics in Fontan circulation influences liver stiffness measurement (LSM) assessed by...

journal_title：Congenital heart disease

authors： Wu FM,Opotowsky AR,Raza R,Harney S,Ukomadu C,Landzberg MJ,Valente AM,Breitbart RE,Singh MN,Gauvreau K,Jonas MM

更新日期：2014-09-01 00:00:00

abstract：:A 52-year-old male patient, with a medical history of surgically repaired double outlet right ventricle presented with severe aortic stenosis (AS) and hepatitis C with cirrhosis, presented with New York Heart Association Class IV heart failure. During evaluation for a liver transplant, he was deemed a poor surgical ca...

journal_title：Congenital heart disease

authors： Keswani A,Verma A,Dann K,Ventura L,Lucas V,Shah S,Ramee S

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Patients with tetralogy of Fallot (TOF) undergoing surgery in adulthood represent a challenge. We report our experience with such patients in or beyond the fourth decade of life. DESIGN:Retrospective cohort. SETTING:Multispeciality tertiary level referral center PATIENTS:Forty-one (age 30-52 years) with TO...

journal_title：Congenital heart disease

authors： Talwar S,Meena A,Choudhary SK,Saxena A,Kothari SS,Juneja R,Airan B

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Cardiopulmonary exercise capacity is often reduced in patients with transposition of the great arteries after atrial switch operation. Reduced exercise capacity may be caused by deterioration of systemic right ventricular function over time. This study analyzed serial changes in systemic right vent...

journal_title：Congenital heart disease

authors： Roentgen P,Kaan M,Tutarel O,Meyer GP,Westhoff-Bleck M

更新日期：2014-05-01 00:00:00

abstract：:Williams-Beuren syndrome (WBS) is a multisystem genetic disorder comprising of craniofacial, developmental, and cardiac malformations. The most common cardiac defects found are supravalvar aortic stenosis and peripheral pulmonary stenosis. However, WBS should be regarded as a general arteriopathy consisting of stenose...

journal_title：Congenital heart disease

authors： Pieles GE,Ofoe V,Morgan GJ

更新日期：2014-05-01 00:00:00

abstract：:Absence of the aortic valve is a rare congenital heart defect that is detectable in the prenatal period. In this condition, functional aortic valve leaflets are absent; in their place are rudimentary, immobile noncoapting plate-like structures at the level of the annulus resulting in severe aortic regurgitation. We re...

journal_title：Congenital heart disease

authors： Sabati AA,Wong PC,Randolph L,Pruetz JD

更新日期：2014-05-01 00:00:00

abstract：:Down syndrome (DS) patients are prone to pulmonary hypertension (PHTN) due to various cardiopulmonary causes. However, the association of DS with pulmonary vein stenosis (PVS) is not adequately described. We illustrate three cases from our center and an additional 13 cases from an extensive review of the literature of...

journal_title：Congenital heart disease

authors： Gowda S,Bhat D,Feng Z,Chang CH,Ross RD

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Surgical management of tetralogy of Fallot (TOF) is increasingly moving toward valve-sparing approaches rather than transannular patch (TAP). We evaluate whether fetal pulmonary valve (PV) size is predictive of postnatal course and surgical approach in TOF. METHODS:In this retrospective study, fetal and pos...

journal_title：Congenital heart disease

authors： Friedman K,Balasubramanian S,Tworetzky W

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:Clinical genetic testing is expanding rapidly, but the application of new testing has not been reported in an unselected, comprehensive congenital heart disease (CHD) patient population. This study aims to identify cytogenetic testing practices and diagnostic yield in infants with CHD as an important first st...

journal_title：Congenital heart disease

authors： Connor JA,Hinton RB,Miller EM,Sund KL,Ruschman JG,Ware SM

更新日期：2014-03-01 00:00:00